Bioimpedance: Innovative Approach in Nephrology and Autoimmune Diseases

Role of Interleukin-37 in Inflammatory and Autoimmune Diseases

Interleukin-1 family 7 (IL-1F7) is a novel member of IL-1F cytokines. IL-1F7 is more commonly known as IL-37. IL-37 join the α-subunit of the IL-18 receptor, or IL-18 binding protein (IL-18BP), and binding of these proteins can enhance the IL-18 suppression. IL-37 also translocates to the cell nucleus and affects gene transcription. IL-37 inhibits the phosphorylation of p38 mitogen-activated pr...

Kidney Diseases beyond Nephrology Kidney diseases beyond nephrology—intensive care

The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) investigators conducted a multinational, multicentre, prospective, epidemiological survey of acute renal failure (ARF) in intensive care unit (ICU) patients [1], with the intention of determining the association between outcome and different epidemiological parameters: period prevalence of ARF, aetiology, illness severity ...

[Innovative Methods of Some Systemic Autoimmune Diseases Treatment].

In the present paper we consider the problem of innovative treatment of systemic autoiminune diseases for example, rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The use of biological therapy is suitable for severe rheumatoid arthritis and promotes remission in 25-30% of cases. Application biological therapy (as anti-B cell therapy) in cases of systemic lupus erythematosus se...

Air Pollution and its Effects on Autoimmune Diseases

P 86: CD166 as a Therapeutic Target in Autoimmune Diseases

About 3 decades ago CD6 identified as one of the first antigens expresses on the majority of T cells and a subset of B cells. CD6 regulates cellular adhesion migration across the endothelial and epithelial cells. In recent years researches indicate its role in pathogenesis of autoimmune diseases. Many researches have been done in recent years to block CD6 by CD6 mono clonal antibodies, IOR-T1 a...